Genova diagnostics sibo8/28/2023 ![]() Genova's SIBO profiles reflect the current state of scientific understanding related to SIBO breath testing and results interpretation – and are designed to optimize management of the symptomatic patient. In general, clinical management of the SIBO patient involves antimicrobial therapy, prokinetic agents, nutrient supplementation, dietary interventions, and treatment of comorbid conditions. What can clinicians and patients expect from the SIBO breath testing? As a result, experts suggest breath testing for the diagnosis of small intestinal bacterial overgrowth. While aspiration of small bowel fluid (followed by culture and bacterial count) is considered to be the current gold standard for diagnosis of SIBO, it is not routinely performed because it requires a complex, invasive technique, and is costly. What advantage does the SIBO breath test offer compared to other diagnostics? Symptomatic patients with any underlying conditions or risk factors warrant assessment for SIBO. Risk factors for development of SIBO include structural/anatomic issues, motility disorders, organ system dysfunction, elderly age and various medications (recurrent antibiotics, PPIs) that alter the gut microflora populations. ![]() Conditions commonly associated with SIBO include: ![]() Symptoms of SIBO are non-specific, encompassing abdominal pain/distention, diarrhea, and flatulence. When should testing for SIBO be considered? The 3-hour SIBO profile provides insight into gas levels over a longer period of time, and is recommended for patients with slower gastrointestinal transit or constipation. Clinicians have the option of a 2 or 3-hour SIBO assessment. Genova's SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the SIBO is a common clinical condition and can develop in a variety of patient populations. Some of those technologies include 16S rRNA PCR, MALDI-TOF, ELISA, microscopic ova and parasite (O&P), Real-time PCR, Next-Generation DNA sequencing, culture analysis, and Tandem Mass-Spectrometry (LC-MS/MS), to name a few.Uncover the Cause of Unexplained Abdominal Symptoms with Breath Testing Many of their comprehensive panels include multiple technologies in the same test. They are licensed by CLIA, the federal agency regulating laboratories, and by those states requiring individual licenses in addition to CLIA. ![]() They are committed to using the most clinically relevant technology to provide actionable results to aid patient treatment. Genova doesn't subscribe to a 'one size fits all approach when it comes to utilizing technology. The Genova Diagnostics Leadership Team combines decades of experience in various areas of the healthcare industry, many with an entire career in integrative and functional medicine. Genova's mission statement is "to be the best provider of comprehensive and innovative clinical laboratory services for the prevention, diagnosis, and treatment of complex chronic disease." They provide testing services to all 50 states and around the world. ![]() Genova Diagnostics was established in 1986 as Great Smokies Diagnostic Laboratory. Many providers turn to Genova tests for treating chronic GI issues, nutritional deficiencies, mood disorders, fatigue, chronic pain & inflammation, weight issues, cardiovascular concerns, and general health optimization. Genova’s SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a Lactulose solution to evaluate small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO). Genova Diagnostics offers a wide array of tests, though their most popular ones are their GI-Effects stool test, NutrEval nutritional test and SIBO breath tests. ![]()
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